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“Don’t just go for safe projects, take on the really tough problems.”

Vision: Be an optimist. Focus on a few big goals that can help every person have a healthy, productive life. Action: Some of the projects the foundation funds will fail. Bill and Melinda Gates not only accept that, they expect it—because they think their essential role is to make bets on promising solutions that governments and businesses can’t afford to make. They adjust strategies and share the results so everyone can benefit. www.GatesFoundation.org